for patients with a known #chromosome rearrangement (#translocations) Its not for everyone- but it can be a #powerful #tool, especially when patients are of a higher #maternal age (over 37), where half or more #embryos are likely to be #chromosomally abnormal
Typical conversions from animal studies use body-surface-area scaling: Rat dose: 10 g/kg human equivalent ( 0.162) 1.6 g/kg For a 70 kg adult: ~112 g per day Self-experiment protocols often cite 100200 g once or twice daily via subcutaneous injection
However, these drugs can lead to adverse effects, including systemic exposure through nasal absorption and localized irritation [84, 85]

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