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Studies on its use in nondiabetics usually adhere to the approved anti-diabetic dosage regimen of 3mg, 7mg, and 14mg, increased or tolerability
The STEP trials are testing semaglutide at the higher dose of 2.4 mg/week (as compared to 1.0 mg/week for the original diabetes indication), specifically for promoting weight loss, regardless of the presence of type 2 diabetes
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