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She ended up eating smaller portions and made lasting changes to her eating habits

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DOI 10.1001/jama.2021.3224 - run-in nausea 47% falling to 14% at maintenance

This creates a flatter pharmacokinetic curve with lower peak levels and higher trough levels, potentially reducing the intensity of receptor desensitization at peak concentrations while maintaining more consistent receptor occupancy throughout the week

I made each version for a full week and tracked not just appetite, but also prep time, flavour, and how I felt afterwards