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The recommended starting dose is 0.25 mg per week, which can be increased to 0.5 mg per week after four weeks if tolerated

The continuous hyperglycemia can induce target organ damage (TOD) by increasing the risk of panvascular disease, including microvascular disease (such as diabetic retinopathy, nephropathy and neuropathy), and atherosclerotic macrovascular disease (cardiovascular, cerebrovascular, and other peripheral vascular diseases)

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Those who receive regular biologics or chemotherapy injections may be able to use a different medication