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Human Trials That Could Advance Practice in the Near-Term Beyond the trials in progress listed at the bottom of this article, there are a number of study questions which we believe could rapidly advance our knowledge for important use cases in the near to mid-term and bring GLP-1s into the clinic faster

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[21] For patients undergoing surgery , the approach should be individualised based on several factors: Aspiration risk assessment : Patients with symptoms of gastroparesis, those on high doses, or those who have recently initiated therapy may have increased risk Type of surgery : Particularly procedures involving the gastrointestinal tract Indication for GLP-1 therapy : Whether for diabetes management or weight loss If GLP-1 medications are temporarily withheld based on individual risk assessment or local policy, patients with diabetes should have a clear plan for glycaemic management, including capillary glucose monitoring and potential bridging therapy, developed in consultation with the diabetes team