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For context, headache rates with tirzepatide and semaglutide are similar or slightly higher, suggesting this is more of a general weight-loss medication effect than something specific to cagrilintide pharmacology
The NOAEL established in 90-day rat toxicology studies is 50mg/kg daily, which translates to a human-equivalent dose of approximately 560mg daily using FDA allometric scaling
Forbes, J
Sammeturi M, Shaik AH, Bongu SBR, Cheemanapalli S, Mohammad A, Kodidhela LD
BPC-157: Commonly cited at 250 to 500 mcg once or twice daily, given subcutaneously or as a local injection
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