Practical tips for abdominal injection of retatrutide: Pinch a fold of skin between your thumb and forefinger, pulling the tissue away from the abdominal wall Insert the needle at a 45 to 90 degree angle depending on the amount of subcutaneous fat (more fat = steeper angle is fine) Inject slowly over 5 to 10 seconds Hold the needle in place for 5 seconds after injection before withdrawing Do not massage the area after injection, this can alter absorption rate Rotate at least 1.5 inches from the previous injection site The anterior thigh: the reliable alternative The front of the thigh provides an excellent alternative injection site, particularly for people who find abdominal injections uncomfortable or who need to rotate away from the abdomen to allow tissue recovery
Latner JD, Wilson GT
Led by Jacob Greenberg, MD, of the Taylor Family Department of Neurosurgery, and Burel Goodin, PhD, of the Department of Anesthesiology at WashU Medicine, in collaboration with Robert Sorge, PhD, and Jake Godzik, MD, at the University of Alabama at Birmingham, researchers will evaluate whether semaglutide can reduce back pain severity and disability in people with chronic low back pain and obesity
This situation is reversed in people with T2D where, although GIP secretion remains largely intact, GIP receptor activity is much reduced
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