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These enzymes are the pyruvate dehydrogenase complex (PDHc) and 2-oxoglutarate (-ketoglutarate) dehydrogenase (OGDH), both of which are associated with the TCA cycle, and branched-chain ketoacid dehydrogenase (BCKD) necessary for metabolism of the branched-chain amino acids, leucine, isoleucine, and valine

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The two delivery routes have different pharmacokinetic profiles in published research

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TM3 cells were seeded in the plate wells, and GC-1 spg cells were placed in the transwell inserts, facilitating indirect interaction