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For survival-curve determinations, tumour-sized-based survival rate methods were applied, with 1.5 cm as the recommended predetermined survival rate per ethically acceptable cut-off values for determining therapeutic efficacy in mouse studies 56

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Growth Factor Modulation (VEGF, TGF-, FGF, GH Receptor, EGR-1, NAB2) Beyond direct angiogenic pathway activation, BPC-157 also influences the expression and activity of various growth factors, which are proteins that regulate cell growth, proliferation, and differentiation