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doi: 10.3390/nu13082613 289

Once-daily dosing offers simplicity and better compliance, while split dosing theoretically maintains more stable tissue concentrations throughout the day

Our recent work demonstrated that oxidized low-density lipoprotein (LDL) upregulates DPP-4 expression on macrophages via activation of Toll-like receptor 4 (TLR4)/TIR-domain-containing adapter-inducing interferon- (TRIF) and CD36 pathways [36]

Omega-3 fatty acids Chronic inflammation increases oxidative stress and can contribute to decreased glutathione levels (9)

There were early post-marketing reports of pancreatitis in a small number of patients on exenatide, which raised concern (especially around 20072008)