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In 1992, researchers isolated exendin-4 from its saliva, a peptide that activates the human GLP-1 receptor, shares ~ 53% sequence homology with human GLP-1, stimulates insulin, regulates glucose, and crucially resists rapid DPP-4 degradation, giving it a ~ 12-hour action

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Maintain consistent sleep and stress management routines

Similar increases in resting heart rate have been documented with liraglutide (Saxenda) and semaglutide (Wegovy/Ozempic), as noted in their respective UK Summaries of Product Characteristics (SmPCs) available via the Electronic Medicines Compendium (eMC)