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BP extracts are used in cosmetics in a concentration of 0.55%
This may suggest an increased risk of hypoglycaemia, however, the proximal tubule retains its glucose reabsorption capacity via the action of the SGLT1 when the filtered glucose load falls below ~80 g/day [11]
This action results in enhanced resistance to both internal and external apoptotic pathways, ultimately contributing to cellular resilience against DNA damage responses [288]
It first drew research interest for its ability to heal stomach ulcers and inflammatory bowel conditions, then expanded to tendon, ligament, muscle, and even bone healing across dozens of preclinical studies (Sikiric et al., PubMed)
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