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[1] Important safety considerations include the risk of pancreatitis (seek urgent medical attention for severe, persistent abdominal pain), gallbladder disease , dehydration leading to acute kidney injury (particularly with vomiting or diarrhoea), and potential worsening of diabetic retinopathy in those with pre-existing disease

This decline can be attributed primarily to increased competition and market dynamics but does not detract from its strong historical performance and established efficacy

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