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GLP-1 (glucagon-like peptide-1) is a hormone-based therapeutic class used to improve insulin secretion and regulate blood sugar levels

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The principal neurological function regulated by GLP-1RA could be summarized as follows ( Figure 2 ): (1) GLP-1RA liraglutide and exendin-4 effectively inhibited neuronal apoptosis ( Figure 2 4 GLP-1RA reduced the risk of stroke in T2D patients clinically As a new type of hypoglycemic drug, GLP-RAs are currently mainly used in clinical practice to evaluate the prognosis of various complications in T2D patients, such as stroke, kidney injury, fatty liver, and cardiovascular disease (43)

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compared to a low bioavailability of 1-2% when taken orally