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The RNA-seq data of normal thyroid tissues were downloaded from the Genotype Tissue Expression (GTEx) database ( In addition, the study downloaded and integrated RRM2 RNA expression data for 30 different cancer types and their corresponding paracancerous tissues from the TCGA and GTEx databases
(February 2000)
found that circ_0001273, as a cancer-promoting factor that upregulates SLC1A5 expression by binding to miR-622, which increases Gln uptake by tumor cells, consequently enhancing tumor growth and inhibiting cell apoptosis (57)
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