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Someones preferences, lifestyle, and ability to take it consistently play a major role, too
as of May 2026
Give any intervention 2 weeks before concluding it is not working
Tirzepatide is a synthetic peptide that mimics two incretin hormones, GLP-1 and GIP, which play critical roles in blood sugar regulation and appetite control
So the weight gain reflects a biological shift, which is why the same diet and exercise that worked before often stop working and a different strategy is needed
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