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Le-Vel likely recommends continuous use to maintain sales, but cycling off periodically might prevent tolerance while saving money
The irritation requires stopping use, waiting for recovery, and restarting at appropriate levels, wasting both time and product
Pues ya lo sabes
These medications work through several mechanisms, including slowing gastric emptying (though this effect may attenuate over time), acting on appetite centers in the hypothalamus, and enhancing feelings of fullness
Bertler A et al (1966): The localization of monoaminergic blood-brain barrier mechanisms
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