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Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications increasingly prescribed for type 2 diabetes management and, more recently, for weight management in adults with obesity
Even in carbohydrate-depleted conditions, the glucagon arm of retatrutide continues to drive hepatic glucose output and thermogenic activity
When the medication enters subcutaneous fat, it creates a small depot
Since GLP-1 agonists are specifically being studied for cardiovascular benefits, ensuring adequate testosterone levels complements rather than contradicts these effects
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