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Metabolic comorbidities are highly prevalent and bidirectionally linked to MASLD: type 2 diabetes, hypertension, dyslipidemia, and chronic kidney disease (CKD) cluster together, collectively amplifying hepatic and systemic disease progression
Presented for research literature review only Xu K et al
Glutathione S-transferase polymorphisms and their biological consequences [PMID: 10971201] Laboratory literature summary: Glutathione S-transferase polymorphisms and their biological consequences
Make sure theres a way to get a quick response from a licensed practitioner (ideally someone trained in obesity medicine) if you dont feel well or have questions, like by messaging through a patient portal
In particular, changes in the expression/function of OCTN2 and CT2 have been observed in human cancers indicating that cell supply of carnitine is strictly regulated during cancer development and that chemical KO of these proteins may serve as a strategy to impair energy production from FAO
