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Other conditions common in people with obesity or diabetes can also contribute to fatigue, including sleep apnoea, thyroid disorders, and depression
Pelletier CC, Croyal M, Ene L, et al
These free radicals contribute to tiredness, weak immunity, faster ageing rate, and cardiovascular problems
Alone or combined with metformin or a thiazolidinedione, exenatide or liraglutide do not cause hypoglycemia
In general, ROS signaling in eryptosis is less diverse compared to nucleated cells, since in erythrocytes, ROS mainly mediate PS externalization by modulating Ca 2+ influx, while in nucleated cells, there are multiple signaling pathways downstream of ROS involved in the execution of apoptosis
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