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That resistance mattered, because your body's own GLP-1 is broken down within minutes
As demonstrated in multiple approved TransCon products, carefully engineered PEG carrier systems can help enable weekly or extended dosing while preserving the activity of the parent drug
So it is never one thing
She also emphasized Mounjaro's weight loss benefits, suggesting that a drug like Mounjaro could be very useful for obese patients who need to lose weight and control their blood sugar at the same time
Outeirino-Iglesias V, Romani-Perez M, Gonzalez-Matias LC, Vigo E, Mallo F (2015) GLP-1 increases preovulatory LH source and the number of mature follicles, as well as synchronizing the onset of puberty in female rats
