doi: 10.1007/s00125-011-2232-3 11 ChenJZhaoHMaXZhangYLuSWangYet al
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Where most therapeutic peptides degrade within minutes under simulated gastric or intestinal conditions, BPC-157 retains its integrity in human gastric juice for more than 24 hours, tolerates a wide pH range, and resists multiple proteolytic enzymes including pepsin and trypsin
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Understanding the broad mechanism of action is essential when considering whether GLP-1 medications might influence hormonal balance more generally, particularly given their increasing use in diverse patient populations including those with metabolic syndrome, polycystic ovary syndrome (PCOS), and obesity-related endocrine dysfunction