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Folinic acid (leucovorin) , methyl-B12 , and antioxidant support have shown positive impact in children with demonstrable metabolic vulnerabilities particularly those with cerebral folate deficiency (CFD) or mitochondrial markers

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Braniste, V

2) Cellular Growth in Human Myotubes In human cell models 4 , IGF-1 directly drives hypertrophy markers (greater nuclei per myotube, higher fusion index, elevated contractile protein content), reinforcing its role in the cellular foundation of strength and size gains

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