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Lipase treatment of dietary krill oil, but not fish oil, enables enrichment of brain eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)

Thus, thiamine, combined with other vitamins of the B complex such as B2 and B3, is vital for the proper functioning of various enzymes involved in key biochemical processes, primarily those related to energy production (, , ) ( Figure 3 )

Significantly affected pathways include transforming growth factor-beta (TGF-beta) signaling, with modulation of SMAD-dependent gene transcription

Other methods are being researched, such as focused ultrasound (FUS), ligand-decorated nanoparticles, exosomes, and lipid-based carriers

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