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Separately, TRANSCEND-T2D-1 part of a distinct three-trial diabetes-specific program confirmed -2.0% HbA1c reduction and 16.8% weight loss in 537 type 2 diabetes patients (topline March 2026, published in The Lancet, June 2026)

I asked the doctor if I could be put in a coma until it was over, she recalled

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For many patients, symptoms improve with continued therapy as the body adapts, though individual experiences vary

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