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Metformin, the most commonly prescribed drug for diabetes, may also increase insulin sensitivity in peripheral tissues during fasting by reducing HGP, which is considered to be mediated by the promotion of mitochondrial activity or the inhibition of glucagon signaling through AMPK activation [160,161]

Haddad M, Stewart J, Xie P, et al

1,6 References Chen, L., Zhu, Y., Hu, Z., et al

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