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These resins come in cationic or anionic forms, allowing for selective exchange of positively or negatively charged ions in a solution

In consideration of the dual roles of GLP-1RAs in hypoglycemic effects and preventing CVD among T2DM patients, we reviewed the cardiovascular effects and molecular mechanisms of GLP-1RAs in CVOTs, animal models and cultured cells, and discuss how these findings transform pharmacotherapies for T2DM, and even expand the indication of this important category of anti-diabetic drugs to CVD patients without diabetes

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doi:10.1016/S0076-6879(05)01005-0

Penelope AE Main, Manya T Angley, Catherine E ODoherty, Philip Thomas and Michael Fenech