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If both are deteriorating, something in the protocol needs adjusting usually recovery or training load
In the liver-fat substudy, beta-hydroxybutyrate, a marker of fat being burned for fuel, rose two to threefold at the higher doses
doi: 10.1002/hep.30652 63 GuCZhouZYuZHeMHeLLuoZet al
If markers remain stable, proceed to introducing retatrutide in week 3 or 4
doi: 10.2174/0115734021398680251001102514 40
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