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The five variables and their respective cut-off values were arranged so as to define three distinct groups of increasing severity (A, B and C)
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Finally, replacing the ChenWhite ligand with the structurally more hindered NordlanderCostas 44 iron-activating ligand produced Fento-5, which exhibited similar cytotoxic and membrane-lipid-oxidation properties to those of Fento-1, albeit with a delayed cell-death response
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