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J Pharmacol Sci 108:227238 Massucci FA, DiNuzzo M, Giove F, Maraviglia B, Castillo IP, Marinari E, De Martino A (2013) Energy metabolism and glutamate-glutamine cycle in the brain: a stoichiometric modeling perspective

In nearly half of all heart attack patients, tiny blood vessels within the heart remain narrowed, even after the main artery is cleared during emergency treatment

The sudden or gradual onset of diffuse mucosal pigmentation in adulthood, even in darkerskinned patients, should alert the clinician to contemplate a pathologic genesis

Off-Label Use on the Rise Despite the promising data, many of these potential benefits fall outside the current FDA-approved uses, which include obesity, Type 2 diabetes, cardiovascular risk reduction, and more recently sleep apnea in some cases

When used concurrently with insulin or insulin secretagogues such as sulfonylureas or meglitinides, the risk of hypoglycemia may be increased, particularly during the initiation of therapy or following dose escalations