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That is the evidence gap, stated plainly: the mechanism is well-motivated and the preclinical signal is consistent, but no human study has confirmed that any of it translates to people, at any dose, by any route
Scientific Reports (2021) 6
Peters, MO, can be a practical tool
This region-specific action is associated with its local stimulation of hormone-sensitive lipase and enhanced fatty acid oxidation, suggesting potential for site-selective metabolic modulation without systemic hormonal changes
Can Vitamin B12 injections be used for patients with neurological manifestations
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