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The volume of chips, sweet bakery goods, cookies, soft drinks, ice cream, candy and chocolate is now substantially lower, with overall spend on these same items tending to stay strong even after starting a GLP-1 regime, suggesting premiumization in consumption

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The STEP 1 trial, which tested semaglutide 2.4mg in adults with obesity, found that approximately 39% of weight lost was lean mass after 68 weeks

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Statins, fibrates, and certain antibiotics can cause myopathy , and their effects may be potentiated by tirzepatide-induced metabolic changes