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Reconsideration of inhibitory effect of metformin on intestinal glucose absorption

UK Clinical Guidance Weight loss injections such as semaglutide (Wegovy) and liraglutide (Saxenda) are increasingly prescribed in the UK for obesity management, but their use in patients with gallstones requires careful consideration

This is also consistent with data from the STEP 9 trial for semaglutide, which showed significant improvements in knee pain scores in adults with obesity and osteoarthritis suggesting a class effect beyond simply the weight loss itself