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Rodriguez-Barrueco R, Latorre J, Devis-Jauregui L, Lluch A, Bonifaci N, Llobet FJ, et al
On the other hand, chronically elevating GIP levels in a transgenic mouse model exhibited reduced diet-induced obesity (69)
reconstitute with sterile diluent for use
Evidence on safety and optimal dosing schedules is limited
Mitochondrial dysfunction leading to oxidative stress also induces FGF21 expression in preclinical disease models (110), while levels of FGF21 are elevated in the circulation and skeletal muscle of patients with myopathies caused by mutations in components of the mitochondrial oxidative phosphorylation machinery (111)
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