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For patients and clinicians, this was a novel mechanism a drug for diabetes that caused weight loss and had low hypo risk was almost unheard of at the time
If irritation occurs, discontinue use and consult a dermatologist
Unlike obese MAFLD, the pathogenesis in lean patients is more complex, potentially involving genetic factors, insulin resistance, and gut microbiota imbalances
In studies combining NNMTi with other weightloss drugs, coadministration with GLP1 receptor agonists significantly enhances weightloss efficacy while reducing side effects such as nausea and vomiting commonly associated with GLP1 agonists
Fouladiun, M
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