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More serious side effects may include severe gastrointestinal issues with the stomach, gallbladder or liver, pancreatitis, kidney failure, hypoglycemia, or depression/thoughts of suicide Zepbound (tirzepatide) causes thyroid C-cell tumors in rats, it is unknown whether it causes such tumors in humans at this time
While it is generally safe for most adults with a BMI over 27, ignoring recommended precautions can lead to side effects, hinder your progress, or compromise your overall health
For instance, in April 2025, Pfizer, a US-based pharmaceutical company specializing in metabolic and cardiometabolic drug development, provided an update on its oral GLP-1 receptor agonist candidate, danuglipron, following the completion of once-daily formulation studies intended to improve dosing convenience for patients
By following these simple tips, you can be confident that your medicine is safe and ready to help you on your journey
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