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Published 2018 Jun 25

GHK-Cu binds to copper and interacts with several biological pathways connected to: Collagen and elastin synthesis supporting the structural proteins responsible for skin firmness Antioxidant activity helping neutralize oxidative stress that accelerates visible aging Anti-inflammatory signaling calming irritation that can slow healing Blood vessel formation (angiogenesis) supporting nutrient delivery to healing tissue Stem cell activation encouraging the migration of skin cells involved in repair Because of these overlapping functions, researchers have studied the peptide not just for cosmetic purposes but for wound healing, post-surgical recovery, and hair follicle stimulation

In activated macrophage cultures, GHK-Cu administration reduces the production of pro-inflammatory cytokines including interleukin-1, tumor necrosis factor-, and interleukin-6 by 40-65% while simultaneously increasing the production of anti-inflammatory mediators such as interleukin-10 and transforming growth factor-

Yes, especially with stronger topical concentrations, oral supplements, or injectable use

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