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The new guidance immediately opens the door for Novo Nordisks Wegovy to gain coverage based on its cardiovascular benefits, following formal FDA approval earlier this month for this indication

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However, no associations between choline or betaine intakes and cardiovascular-related mortality were found in a cohort study of Japanese adults (n=29,079) (45)

Comparison of the cardiovascular outcomes of GLP-1RAs and SGLT2 inhibitors may help the clinician to select the best personalised treatment approach for patients with type 2 diabetes [38]