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One well-documented interaction is with certain anti-epileptic drugs: high-dose pyridoxine may reduce the plasma levels of phenytoin and phenobarbital by enhancing their hepatic metabolism, potentially diminishing their anticonvulsant efficacy

They are usually safe but can cause problems for some people

When To Take High-Dose Vitamin B12 Supplements Treating Vitamin B12 Deficiency People take high-dose vitamin B12 to treat a vitamin deficiency (levels below 200 to 250 pg/mL)

Lipo B12 and AMINO injections have gained attention for their potential benefits in weight loss, energy boost, and overall well-being

Are Lipotropic B12 Injections Dangerous