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Biological evaluation included in vitro cytotoxicity tests on HepG2, intestinal epithelial cell line (Caco-2), and dopaminergic neurons (Differentiated SH-SY5Y with 0.1% retinoic acid) cell lines, showing low cytotoxicity
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Growth hormone secretagogues have a potentially lower risk
In laboratory research, IGF-1 LR3 is used to investigate growth factormediated signaling pathways that regulate cellular proliferation, differentiation, metabolism, and protein synthesis
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