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It depends on the protocol format
Non-oral therapies have, therefore, been actively investigated and developed over the past decade, key successes being the transdermal rotigotine (RTG) patch, infusional therapies with apomorphine, intrajejunal levodopa, and the apomorphine pen strategy, all of which are currently in clinical use
Many people, however, are exposed to larger quantities of this smelly gas, quantities that are more toxic than beneficial (Blachier et al., 2007
Hughes, R
As all major obesity guidelines emphasize, lifestyle-based behavioral therapy remains the first-line foundation of care, with pharmacotherapy used as an adjunct rather than a replacement [35,36,37]
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