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In people with cirrhosis or advanced liver dysfunction, unmonitored NAD+ therapy may worsen their condition or cause unexpected side effects
This is where the conversation gets interesting
Unfortunately, natural NAD+ levels decline significantly as we age[2], often dropping by up to 50% by the time we reach our fifties
Moreover, the greater lean mass and mechanical loading typically observed in males may provide partial protection against CR-induced bone resorption
Because they are not regulated, there is no guarantee that the ingredients on the label match what is actually inside the product
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