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Alanine at position 8 of native GLP-1 is replaced with 2-aminoisobutyric acid, also known as Aib, which increases resistance to enzymatic degradation by dipeptidyl peptidase-4
While NAC is generally safe, some individuals may experience gastrointestinal discomfort or allergic reactions
Dispose of materials per applicable waste regulations and institutional policy
Discontinued and pipeline GLP-1 medications Discontinued: Albiglutide (Tanzeum): Approved 2014, voluntarily withdrawn 2018
21 (1), e12964
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