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The trade is explicit: the patient gives up the possibility of insurance subsidy, and in exchange gets pricing certainty, no prior-authorization gauntlet, and continuity that does not reset every time an employer renegotiates its formulary
It is a recalibrated palate
Ann Pharmacother (2020) 54(5):47885
Sample overlap bias in forward analysis The results indicated a slight increase in both bias and type I error with an in-creasing rate of sample duplication
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