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intro Tirzepatide is a dual GIP and GLP-1 receptor agonist manufactured by Eli Lilly, available under two brand names: Zepbound (FDA-approved for chronic weight management and obstructive sleep apnea) and Mounjaro (FDA-approved for type 2 diabetes)
In the UK, the MHRA has approved semaglutide (Wegovy) and liraglutide (Saxenda) specifically for weight management in adults with obesity or overweight with weight-related comorbidities (as per NICE TA875 and TA664)
Currently licensed standard-dose diabetes tablets in the UK generally yield lower average weight loss results than dedicated weight loss injections
Monitoring for adequate nutrition, hydration, and electrolyte balance is essential during treatment
doi: 10.1007/s11101-023-09909-5 109 FrazziniSTorresaniMCRodaGDellAnnoMRuffoGRossiL
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