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A 2024 study in Health Affairs (Wharam et al.) found that 89% of appeals for weight-loss medication denials based on plan exclusions were unsuccessful, compared to 54% success rate for appeals based on insufficient documentation
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Things they once craved are no longer appealing, while new cravings developed for healthier foods
This factor appears to be specific to MS because even more prominent meningeal inflammation in the context of bacterial meningitis for instance, does not induce such pathology (Junker et al., 2020)
What Happens to Weight and Health
