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If you are on bupropion 300mg daily and develop significant GI side effects from tirzepatide that lead to dehydration, your seizure risk climbs
Your provider can weigh adoption trends and popularity against your personal medical profile to determine true clinical appropriateness
Whilst no formal pharmacokinetic interaction is listed, the opposing effects on appetite and potential for compounded side effects raise clinically important concerns
By increasing the dose too rapidly the likelihood of side effects increases
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