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A broad panel of antibodies was employed, including those for FOXO4, p53, phospho-p53, p21, p16, cleaved-Caspase3, BAX, BCL-2, testosterone synthesis enzymes (3-HSD, CYP11A1, CYP17A1), and various SASP factors (IL-1, IL-6, TNF-, TGF-)
The H-spelling reflects the relationship to the parent natural complex epithalamin
Each sample group contained at least 10 million endothelial cells
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Cagrilintide mimics amylin, a hormone co-secreted with insulin from pancreatic beta cells, reducing food intake and delaying gastric emptying through a complementary but mechanistically distinct pathway
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