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Further research is needed to elucidate the basic mechanism underpinning T and B-cell recruitment into an immune response, to examine antibody affinity maturation and to identify the determinants of the immunodominance hierarchy for T and B-cell epitopes, which ultimately may enable vaccine antigens to be rationally designed to induce broadly targeted immunity
Discontinued Therapeutics for NASH Over the last few years, several pharmaceutical companies have failed to find a drug for the treatment of NASH typically because of a lack of efficacy, toxicity or elements of both
Long-term graft function of adult rat and human islets encapsulated in novel alginate-based microcapsules after transplantation in immunocompetent diabetic mice
GLP-1 receptor agonists should not be used in combination with DPP-4 inhibitors (such as sitagliptin), as both act on the incretin system
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