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Parallel evolutionary pathways for glutathione transferases: structure and mechanism of the mitochondrial class kappa enzyme rGSTK1-1
Current estimates suggest: Approximately 900,000 people living with dementia in the UK (Alzheimer's Society) Two-thirds of these have Alzheimer's disease (approximately 600,000 people) Projected to rise to 1.6 million by 2040 as the population ages Healthcare and social care costs exceed 26 billion annually Informal caregiving burden is enormous, affecting family members' employment and wellbeing This disease burden explains why the NHS and research community continue pursuing disease-modifying treatments, despite repeated setbacks like the LIFT-AD trial failure
Saxenda is one of the GLP-1 medications prescribed by Calibrate clinicians
2014;11: 202230
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